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Effects of Physical Activity on Depressive and Anxiety Symptoms in Women During Menopause: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Trials

The international journal of behavioral nutrition and physical activity
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Hongyu Yue, Yijiao Yang, Fangfang Xie, Jiahe Cui, Yang Li, Mengran Si, Shanshan Li, Fei Yao

In a significant development, researchers from Shanghai have uncovered compelling evidence that physical activity (PA) can substantially alleviate depressive and anxiety symptoms in women experiencing menopause. This research, conducted by a team from the Shanghai University of Traditional Chinese Medicine, highlights an accessible, non-pharmacological intervention that could enhance the quality of life for millions of women worldwide.


Key Findings

  • The study is a comprehensive systematic review and meta-analysis, incorporating 21 randomized controlled trials with a total of 2,020 participants.
  • Women who engaged in physical activity experienced a statistically significant reduction in depressive symptoms, with a standardized mean difference (SMD) of -0.66.
  • Anxiety symptoms also decreased notably among women participating in physical activity, with an SMD of -0.55.
  • Physical activities of low to moderate intensity, such as walking and tai chi, proved particularly effective in managing these symptoms.

"Physical activities of low to moderate intensity can lead to remarkable improvements in managing depression and anxiety among menopausal women." - Study Authors


Why It Matters

Menopause is a natural biological process marking the end of a woman's reproductive years, often accompanied by various physical and emotional symptoms. Depression and anxiety are among the most prevalent mental health challenges during this phase, significantly impacting overall well-being. Traditional treatment options, such as hormone therapy and antidepressants, come with potential risks and side effects. This study emphasizes physical activity as a safe and effective alternative that not only benefits mental health but also offers numerous physical health advantages.

"In addition to traditional treatment strategies like hormone therapy, antidepressants, and psychotherapy, physical activity has been increasingly studied." - Study Authors


Research Details

The research team conducted an extensive review of existing literature, analyzing data from multiple databases, including PubMed, Embase, and Cochrane Library. The studies selected for this meta-analysis focused on the effects of various forms of physical activity on depressive and anxiety symptoms among menopausal women.

Inclusion criteria were stringent, ensuring that only high-quality, randomized controlled trials were considered. The types of physical activities examined ranged from aerobic and resistance training to more holistic approaches like tai chi. The findings were analyzed using the Newcastle-Ottawa Scale to assess the quality and reliability of the studies.

"Physical activity provides a range of health benefits, reducing the risk of coronary artery disease, hypertension, diabetes, obesity, and osteoporosis." - Study Authors


Looking Ahead

This study paves the way for future research to explore the specific types and durations of physical activity that are most beneficial for menopausal women. It also highlights the need for awareness campaigns and programs that encourage physical activity as a viable intervention for mental health during menopause.

Healthcare providers may consider integrating physical activity recommendations into their treatment plans for menopausal women, offering a holistic approach to managing mental health. Further studies could investigate the long-term benefits of sustained physical activity throughout menopause and beyond.

By emphasizing non-pharmacological interventions, this research aligns with a growing trend toward personalized and patient-centered healthcare. As we continue to explore the complexities of menopause and mental health, physical activity emerges as a straightforward yet powerful tool in the fight against depression and anxiety.


In conclusion, the findings from the Shanghai University of Traditional Chinese Medicine provide a hopeful perspective on managing menopausal symptoms. As more women experience the benefits of physical activity, society stands to gain from healthier, happier populations.

Longevity