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Independent and Combined Associations of Physical Activity in Different Domains and Inflammatory Diet with Type 2 Diabetes: A Population-Based Cohort Study.

Nutrients
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Jianfan Zhou, Shuting Yin, Litao Du, Xiangli Xue, Qiang He, Na Zhao, Si Chen, Xianliang Zhang

In a significant advancement in diabetes research, a team from Shandong University has found that combining physical activity with an anti-inflammatory diet is linked to a lower risk of developing Type 2 Diabetes Mellitus (T2DM). This study, which utilizes data from the National Health and Nutrition Examination Study (NHANES), sheds light on strategies to combat one of the most common chronic diseases worldwide.


Key Findings

  • Physical Activity Across Domains: Engaging in regular moderate to vigorous physical activity (MVPA) in work, recreational, and overall contexts is associated with a decreased risk of T2DM.
  • Diet Matters: An inflammatory diet is correlated with a heightened risk of developing T2DM.
  • Combined Impact: The most substantial risk reduction for T2DM was noted when an active lifestyle was paired with an anti-inflammatory diet.

"Our study emphasizes that the combination of active physical activity and an anti-inflammatory diet is closely associated with a reduced risk of T2DM," said lead author Jianfan Zhou.

Why It Matters

Type 2 Diabetes Mellitus presents a major public health challenge globally, often leading to severe complications such as cardiovascular disease, nerve damage, and kidney disease. Identifying modifiable lifestyle factors that can prevent or mitigate T2DM is essential. This study underscores the significance of an active lifestyle and a nutritious diet in lowering diabetes risk, reinforcing the importance of comprehensive health strategies.

"The combination of active and anti-inflammatory elements within the Work MVPA, Recreational MVPA, and Total MVPA categories was associated with the greatest reduction in T2DM risk," the research team noted.

Research Details

This extensive study analyzed data from 8,736 American adults collected by NHANES between 2007 and 2016. Researchers assessed participants' physical activity using the Global Physical Activity Questionnaire, focusing on three domains: Work MVPA, Walk/Bicycle MVPA, and Recreational MVPA. Dietary habits were evaluated through 24-hour dietary recalls, with the inflammatory potential of diets measured using the Dietary Inflammatory Index (DII).

Participants were classified as diabetic based on various criteria, including self-reported diagnosis, medication use, and specific blood glucose and HbA1c levels. The study employed a multivariate modified Poisson regression model to explore the independent and combined effects of MVPA and dietary inflammation on diabetes risk.

Looking Ahead

The findings of this study advocate for integrated lifestyle interventions as a fundamental component of diabetes prevention strategies. Healthcare providers and policymakers are encouraged to highlight the dual benefits of physical activity and diet in public health campaigns. Future research could delve deeper into the mechanisms behind these associations and assess the effectiveness of specific intervention programs.

"This suggests the combination of both for the prevention and treatment of T2DM," the research team concluded.

By adopting a lifestyle that includes regular physical activity and a diet low in inflammatory foods, individuals may reduce their risk of developing Type 2 Diabetes. This research lays the groundwork for future studies and public health initiatives aimed at addressing the diabetes epidemic.

Longevity